Description
Product Characteristics: A disintegrin and metalloproteinase with thrombospondin motifs 2 antibody, A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 2 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 2 antibody, ADAM TS 2 antibody, ADAM TS2 antibody, ADAM-TS 2 antibody, ADAM-TS2 antibody, ADAMTS 3 antibody, ADAMTS-2 antibody, ADAMTS2 antibody, ATS2_HUMAN antibody, EC 3.4.24.14 antibody, EDS VIIB antibody, EDS VIIC antibody, hPCPNI antibody, NPI antibody, PC I NP antibody, PC I-NP antibody, PCINP antibody, PCPNI antibody, pNPI antibody, Procollagen I N proteinase antibody, Procollagen I N-proteinase antibody, Procollagen I/II amino propeptide processing enzyme antibody, Procollagen I/II amino propeptide-processing enzyme antibody, Procollagen N endopeptidase antibody, Procollagen N-endopeptidase antibody
Target Information: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]